Gametes (spermatozoa and oocytes) and embryos from domestic animals are routinely handled in vitro in large and increasing numbers all over the world. Such manipulation causes various forms of damage to the gametes/embryos that can lead to different problems. A safe and reliable basis for continued practical use of these technologies in science and cattle industry requires further activities in research and development. Just as important is a continued close relation between science and industry so that the extent and results of this work can be collected, analyzed and reported for the benefit of all groups involved and interested such as scientists, consumers, industry and legislators