Testicular morphometry of rats with Walker 256 tumor supplemented with L-glutamine
Nayara Rodrigues Rocha; Janine Karla França da Silva Braz; Sara Raquel Garcia de Souza; Luciane Fracaro; Fabiana Cristina Silveira Alves de Melo; Jacqueline Nelisis Zanoni; Naianne Kelly Clebis; Danielle Barbosa Morais; Carlos Eduardo Bezerra de Moura
Abstract
Keywords
References
Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec. 1946;94(2):239-47.
Adra N, Einhorn LH. Testicular cancer update. Clin Adv Hematol Oncol. 2017;15(5):386-96. PMid:28591093.
Amann RP. Reproductive capacity of dairy bulls. IV. Spermatogenesis and testicular germ cell degeneration. Am J Anat. 1962;110(1):69-78.
Banks FCL, Knight GE, Calvert RC, Turmaine M, Thompson CS, Mikhailidis DP, Morgan RJ, Burnstock G. Smooth muscle and purinergic contraction of the human, rabbit, rat, and mouse testicular capsule. Biol Reprod. 2006;74(3):473-80.
Bartlett JMS, Weinbauer GF, Nieschlag E. Stability of spermatogenic synchronization achieved by depletion and restoration of vitamin A in rats. Biol Reprod. 1990;42(4):603-12.
Bergh A, Collin O, Lissbrant E. Effects of acute graded reductions in testicular blood flow on testicular morphology in the adult rat. Biol Reprod. 2001;64(1):13-20.
Berndston WE. Methods for quantifying mammalian spermatogenesis: a review. J Anim Sci. 1977;44(5):818-33.
Boligon CS, Huth A. O impacto do uso de glutamina em pacientes com tumores de cabeça e pescoço em tratamento radioterápico e quimioterápico. Rev Bras Cancerol. 2011;57(1):31-8.
Braz JF, Gomes VA, Siman VA, Matta SLP, Clebis NK, Oliveira MF, Morais DB, Moura CEB. Spermatogenesis in Mdx mouse model of Duchenne muscular distrophy. Anal Quant Cytopathol Histpathol. 2018;40:125-31.
Brito NM, Brito MV, Carvalho RK, Matos LT, Veloso TS, Vasconcelos DM, Brito RB. Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats. Acta Cir Bras. 2007;22(6):495-8.
Calderón Guzmán D, Bratoeff E, Ramírez López E, Hernández García E, Pierdant Rioja F, Osnaya Brizuela N, Trujillo Jiménez F, Barragán Mejía G, Juárez Olguín H, Santamaría del Ángel D. Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate. Andrologia. 2011;43(4):225-32.
Cella PS, Marinello PC, Borges FH, Ribeiro DF, Chimin P, Testa MTJ, Guirro PB, Duarte JA, Cecchini R, Guarnier FA, Deminice R. Creatine supplementation in Walker-256 tumor-bearing rats prevents skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling. Eur J Nutr. 2020;59(2):661-9.
Chen W-J, Huang C-Y, Huang Y-H, Wang S-C, Hsieh T-Y, Chen S-L, Sung W-W, Lee T-H. Correlations between Mortality-to-Incidence Ratios and Health Care Disparities in Testicular Cancer. Int J Environ Res Public Health. 2019;17(1):130.
Cruzat VF, Petry ÉR, Tirapegui J. Glutamina: aspectos bioquímicos, metabólicos, moleculares e suplementação. Rev Bras Med Esporte. 2009;15(5):392-7.
Cruzat VF, Rogero MM, Borges MC, Tirapegui J. Aspectos atuais sobre estresse oxidativo, exercícios físicos e suplementação. Rev Bras Med Esporte. 2007;13(5):336-42.
Davis JR, Langford GA. Response of the testicular capsule to acetylcholine and noradrenaline. Nature. 1969;222(5191):386-7.
Fawcett DW, Neaves WB, Flores MN. Comparative observations on intertubular lymphatics and the organization of the interstitial tissue of the mammalian testis. Biol Reprod. 1973;9(5):500-32.
Fleishman SB, Khan H, Guarino MJ, Suhail M, Strebel RA, Homel P, Rosenwald V, Mirzoyev T, Wozniak TF, Suppiah K. Testosterone levels and quality of life (QoL) in male patients with hormone-independent cancers (HIC). J Clin Oncol. 2010;28(15 suppl):9140-9140.
França L, Russell L. The testis of domestic mammals. Madrid: Churchill Livingstone; 1998.
Ghosh S, Bartke A, Grasso P, Reichert LE Jr, Russell LD. Structural manifestations of the rat sertoli cell to hypophysectomy: a correlative morphometric and endocrine study. Endocrinology. 1992;131(1):485-97.
Gomes-Marcondes MCC, Ventrucci G, Toledo MT, Cury L, Cooper JC. A leucine-supplemented diet improved protein content of skeletal muscle in young tumor-bearing rats. Braz J Med Biol Res. 2003;36(11):1589-94.
Goswami S, Kandhare A, Zanwar AA, Hegde MV, Bodhankar SL, Shinde S, Deshmukh S, Kharat R. Oral L-glutamine administration attenuated cutaneous wound healing in Wistar rats. Int Wound J. 2016;13(1):116-24.
Griswold MD, McLean D. Sertoli cell biology. In: Skinner MK, Griswold MD, editors. Sertoli cell biology. Cambridge: Academic Press; 2005. p. 95-106.
Guarnier FA, Cecchini AL, Suzukawa AA, Maragno ALGC, Simão ANC, Gomes MD, Cecchini R. Time course of skeletal muscle loss and oxidative stress in rats with walker 256 solid tumor. Muscle Nerve. 2010;42(6):950-8.
Hirai S, Naito M, Terayama H, Qu N, Kuerban M, Musha M, Ikeda A, Miura M, Itoh M. The origin of lymphatic capillaries in murine testes. J Androl. 2012;33(4):745-51.
Hirai S, Naito M, Terayama H, Qu N, Kuerban M, Musha M, Itoh M. Lymphangiogenesis in chronic inflammation in the testis. Andrology. 2013;1(1):147-54.
Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA. 2019. SEER cancer statistics review, 1975-2016. USA: National Cancer Institute.
Johnson L, Petty CS, Neaves WB. A new approach to quantification of spermatogenesis and its application to germinal cell attrition during human spermiogenesis. Biol Reprod. 1981;25(1):217-26.
Jones HB, Betton GR, Bowdler AL, McFarquhar RL, Middleton BJ, Lunglmayr G. Pathological and morphometric assessment of testicular parameters in patients with metastatic prostate cancer following treatment with either the antiandrogen Casodex (ZM176,334) or bilateral orchidectomy. Urol Res. 1994;22(3):191-5.
Lara NLM, Costa GMJ, Avelar GF, Lacerda SMSN, Hess RA, de França LR. Testis physiology-overview and histology. In: Skinner MK, editor. Encyclopedia of reproduction. USA: Elsevier; 2018. p. 105-16.
Lira FS, Gonçalves D, Silvério R, Zanchi NE, Nicastro H, Shimura Yamashita A, Donatto F, Rodrigues B, De Oliveira Marques SO, Souza CT, Seelaender M. Estratégias nutricionais no tratamento da síndrome da caquexia associada ao câncer. Rev. Inova Saúde. 2012;1:146-65.
Lousan N, Toledo MT. Evolução do crescimento tumoral e da mobilização dos substratos metabólicos em machos Wistar implantados com Tumor de Walker 256. Revista Eletrônica de Biologia. 2012;5(1):81-99.
Martignoni ME, Kunze P, Friess H. Cancer cachexia. Mol Cancer. 2003;2(1):36-8.
Matés JM, Pérez-Gómez C, Núñez de Castro I, Asenjo M, Márquez J. Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death. Int J Biochem Cell Biol. 2002;34(5):439-58.
Medina MA, Sánchez-Jiménez F, Márquez J, Rodríguez Quesada A, Núñez de Castro I. Relevance of glutamine metabolism to tumor cell growth. Mol Cell Biochem. 1992;113(1):1-15.
Meistrich ML, Eng VWS, Loir M. Temperature effects on the kinetics of spermatogenesis in the mouse. Cell Prolif. 1973;6:379-93.
Middendorff R, Müller D, Mewe M, Mukhopadhyay AK, Holstein AF, Davidoff MS. The tunica albuginea of the human testis is characterized by complex contraction and relaxation activities regulated by cyclic GMP. J Clin Endocrinol Metab. 2002;87(7):3486-99.
Montemurro DG. The effect of nitrofurazone on the testes and accessory sex organs of normal rats and rats bearing the walker carcinoma 256. Br J Cancer. 1960;14(2):319-26.
Montrose DC, Galluzzi L. Drugging cancer metabolism: expectations vs. reality. Int Rev Cell Mol Biol. 2019;347:1-26.
Moraes SP, Cunha A, Reis JA No, Barbosa H, Roncolatto CAP, Duarte RF. Modelo experimental de tumor de Walker. Acta Cir Bras. 2000;15(4):237-42.
Morais DB, De Paula TAR, Barros MS, Balarini MK, De Freitas MBD, Da Matta SLP. Stages and duration of the seminiferous epithelium cycle in the bat Sturnira lilium. J Anat. 2013;222(3):372-9.
Neuman, R.E., Mccoy, T.A. Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine. Science. 1956;124(3212):124-5.
Olaniyi KS, Amusa OA, Oniyide AA, Ajadi IO, Akinnagbe NT, Babatunde SS. Protective role of glutamine against cadmium-induced testicular dysfunction in Wistar rats: involvement of G6PD activity. Life Sci. 2020;242:117250.
Pande M, Flora SJS. Lead induced oxidative damage and its response to combined administration of α-lipoic acid and succimers in rats. Toxicology. 2002;177(2-3):187-96.
Paskins-Hurlburt AJ, Hollenberg NK, Abrams HL. Tumor perfusion in relation to the rapid growth phase and necrosis: studies on the walker carcinoma in the rat testicle. Microvasc Res. 1982;24(1):15-24.
Predes FS, Diamante MAS, Dolder H. Testis response to low doses of cadmium in Wistar rats. Int J Exp Pathol. 2010;91(2):125-31.
Punab M, Poolamets O, Paju P, Vihljajev V, Pomm K, Ladva R, Korrovits P, Laan M. Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts. Hum Reprod. 2017;32(1):18-31.
Rosiepen G, Chapin RE, Weinbauer P. The Duration of the Cycle of the Seminiferous Epithelium is Altered by Administration of 2,5-Hexanedione in the Adult Sprague-Dawley Rat. J Androl. 1995;16:127-35.
Rotovnik Kozjek N, Kompan L, Žagar T, Mrevlje Ž. Influence of enteral glutamine on inflammatory and hormonal response in patients with rectal cancer during preoperative radiochemotherapy. Eur J Clin Nutr. 2017;71(5):671-3.
Rowbottom DG, Keast D, Morton AR. The emerging role of glutamine as an indicator of exercise stress and overtraining. Sports Med. 1996;21(2):80-97.
Russell LD, Ettlin RA, Hikim APS, Clegg ED. Histological and histopathological evaluation of the testis. Int J Androl. 1993;16(1):83-83.
Russell LD, Lee IP, Ettlin R, Malone JP. Morphological pattern of response after administration of procarbazine: alteration of specific cell associations during the cycle of the seminiferous epithelium of the rat. Tissue Cell. 1983;15(3):391-404.
Santos A, Novaes MG. Qualidade de Vida de Pacientes com Câncer Colorretal em Uso de Glutamina. Rev Bras Cancerol. 2011;57(4):541-6.
Savarese DMF, Savy G, Vahdat L, Wischmeyer PE, Corey B. Prevention of chemotheraphy and radiation toxicity with glutamine. Cancer Treat Rev. 2003;29(6):501-13.
Setchell BP, Breed WG. Anatomy, vasculature, and innervation of the male reproductive tract. In: Neill J, Challis J, de Kretser D, Pfaff D, Richards J, Plant T, Wassarman P, editors. Knobil and Neill’s physiology of reproduction. USA: Elsevier Inc., 2006. p. 771-825.
Sharpe RM. Possible role of elongated spermatids in control of stage‐dependent changes in the diameter of the lumen of the rat seminiferous tubule. J Androl. 1989;10(4):304-10.
Shaughnessy SG, Lafrenie RM, Buchanan MR, Podor TJ, Orr FW. Endothelial cell damage by Walker carcinosarcoma cells is dependent on vitronectin receptor-mediated tumor cell adhesion. Am J Pathol. 1991;138(6):1535-43. PMid:1711295.
Silva LFG, Soares FSD, Anselmo JNN, Fé DMM, Cavalcante JLBG, Moraes MO, Vasconcelos PRL. Modelo de tumor experimental em rim de ratos. Acta Cir Bras. 2002;17(1):62-6.
Silva SFMD, Silva CHS, Dias FCR, Cordero-Schmidt E, Vargas-Mena JC, Silva IGMD, Báo SN, Carvalho TG, Araújo Júnior RF, Moura CEB, Melo FCSA, Matta SLPD, Morais DB. Testicular characterization and spermatogenesis of the hematophagous bat Diphylla ecaudata. PLoS One. 2019;14(12):e0226558. http://dx.doi.org/10.1371/journal.pone.0226558.
Simpkins H, Lehman JM, Mazurkiewicz JE, Davis BH. A morphological and phenotypic analysis of Walker 256 cells. Cancer Res. 1991;51(4):1334-8. PMid:1997171.
Sinha-Hikim AP, Bartke A, Russell LD. Morphometric studies on hamster testes in gonadally active and inactive states: light microscope findings. Biol Reprod. 1988;39(5):1225-37.
Smith ZL, Werntz RP, Eggener SE. Testicular cancer: epidemiology, diagnosis, and management. Med Clin North Am. 2018;102(2):251-64.
Suarez-Ibarrola R, Abufaraj M, Shariat SF. Intermediate and long-term complications associated with adjuvant chemotherapy for stage I germ cell tumor patients. Curr Opin Urol. 2018;28(5):485-90.
Teuwen LA, Geldhof V, Carmeliet P. How glucose, glutamine and fatty acid metabolism shape blood and lymph vessel development. Dev Biol. 2019;447(1):90-102.
Yoshida S, Kaibara A, Ishibashi N, Shirouzu K. Glutamine supplementation in cancer patients. Nutrition. 2001;17(9):766-8.
Submitted date:
12/01/2020
Accepted date:
06/22/2021