Animal Reproduction (AR)
https://animal-reproduction.org/article/doi/10.1590/1984-3143-AR2024-0059
Animal Reproduction (AR)
Thematic Section: X International Symposium on Animal Biology of Reproduction (ISABR)

Approaches to improve in vitro survival, growth, and maturation of caprine oocytes: main results from LAMOFOPA-Brazil

José Ricardo de Figueiredo; Ana Flávia Bezerra da Silva; Laritza Ferreira de Lima

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Abstract

This brief review delves into the topic of in vitro follicle culture for in vitro embryo production, with a particular emphasis on goat models. Specifically, we examine the main findings from LAMOFOPA-Brazil over the last 20 years, highlighting the challenges posed by oxidative stress and epigenetic changes. Our focus is on strategies to improve follicular development and oocyte maturation. Furthermore, we underscore the valuable role of the antioxidant anethole in optimizing the efficacy of in vitro follicle culture and improving outcomes in in vitro embryo production.

Keywords

anethole, oocyte growth, in vitro follicle culture, caprine

References

Alves AM, Chaves RN, Rocha RM, Lima LF, Andrade PM, Lopes CA, Souza CE, Moura AA, Campello CC, Báo SN, Smitz J, Figueiredo JR. Dynamic medium containing growth differentiation factor-9 and FSH maintains survival and promotes in vitro growth of caprine preantral follicles after long-term in vitro culture. Reprod Fertil Dev. 2013;25(6):955-65. http://doi.org/10.1071/RD12180. PMid:23050662.

Brito IR, Silva GM, Sales AD, Lobo CH, Rodrigues GQ, Sousa RF, Moura A, Calderón C, Bertolini M, Campello CC, Smitz J, Figueiredo JR. Fibrin-alginate hydrogel supports steroidogenesis, in vitro maturation of oocytes and parthenotes production from caprine preantral follicles cultured in group. Reprod Domest Anim. 2016;51(6):997-1009. http://doi.org/10.1111/rda.12779. PMid:27650787.

Cadenas J, Leiva-Revilla J, Vieira LA, Apolloni LB, Aguiar FLN, Alves BG, Lobo CH, Rodrigues APR, Apgar GA, Smitz J, Figueiredo JR, Maside C. Caprine ovarian follicle requirements differ between preantral and early antral stages after IVC in medium supplemented with GH and VEGF alone or in combination. Theriogenology. 2017;87:321-32. http://doi.org/10.1016/j.theriogenology.2016.09.008. PMid:27729112.

Conceição-Santos AL, Ferreira ACA, Sá NAR, Palomino GJQ, Silva AFB, Oliveira AC, Velarde JMDS, Celestino JJH, Rodrigues APR, Figueiredo JR. Anethole supplementation during in vitro maturation increases in vitro goat embryo production in a concentration-dependent manner. Theriogenology. 2024;215:78-85. http://doi.org/10.1016/j.theriogenology.2023.11.024. PMid:38016304.

Correia HHV, Lima LF, Sousa FGC, Ferreira ACA, Cadenas J, Paes VM, Alves BG, Shikanov A, Figueiredo JR. Activation of goat primordial follicles in vitro: influence of alginate and ovarian tissue. Reprod Domest Anim. 2020;55(1):105-9. http://doi.org/10.1111/rda.13582. PMid:31661715.

Eppig JJ, Schroederc AC. Capacity of mouse oocytes from preantral follicles to undergo embryogenesis and development to live young after growth, maturation, and fertilization in vitro. Biol Reprod. 1989;41(2):268-76. http://doi.org/10.1095/biolreprod41.2.268. PMid:2508774.

Ernst EH, Grøndahl ML, Grund S, Hardy K, Heuck A, Sunde L, Franks S, Andersen CY, Villesen P, Lykke-Hartmann K. Dormancy and activation of human oocytes from primordial and primary follicles: molecular clues to oocyte regulation. Hum Reprod. 2017;32(8):1684-700. http://doi.org/10.1093/humrep/dex238. PMid:28854595.

Ferreira ACA, Cadenas J, Sá NAR, Correia HHV, Guerreiro DD, Lobo CH, Alves BG, Maside C, Gastal EL, Rodrigues APR, Figueiredo JR. In vitro culture of isolated preantral and antral follicles of goats using human recombinant FSH: concentration-dependent and stage-specific effect. Anim Reprod Sci. 2018;196:120-9. http://doi.org/10.1016/j.anireprosci.2018.07.004. PMid:30049427.

Ferreira ACA, Sá NAR, Silva RF, Sousa FGC, Anjos JC, Cadenas J, Alves BG, Lima LF, Celestino JJH, Gastal MO, Rodrigues APR, Gastal EL, Figueiredo JR. In vitro- and in vivo-derived early antral follicles have comparable in vitro follicular growth and oocyte maturation rates in goats. Theriogenology. 2022;188:135-44. http://doi.org/10.1016/j.theriogenology.2022.05.013. PMid:35689943.

Figueiredo JR, de Lima LF, Silva JRV, Santos RR. Control of growth and development of preantral follicle: insights from in vitro culture. Anim Reprod. 2018;15(1, Suppl 1):648-59. http://doi.org/10.21451/1984-3143-AR2018-0019. PMid:36249835.

Lima IM, Celestino JJ, Faustino LR, Magalhães-Padilha DM, Rossetto R, Brito IR, Donato MA, Lopes CA, Campello CC, Peixoto CA, Figueiredo JR, Rodrigues AP. Dynamic medium containing kit ligand and follicle-stimulating hormone promotes follicular survival, activation, and growth during long-term in vitro culture of caprine preantral follicles. Cells Tissues Organs. 2012;195(3):260-71. http://doi.org/10.1159/000325150. PMid:21494023.

Liu J, Van der Elst J, Van den Broecke R, Dhont M. Live offspring by in vitro fertilization of oocytes from cryopreserved primordial mouse follicles after sequential in vivo transplantation and in vitro maturation. Biol Reprod. 2001;64(1):171-8. http://doi.org/10.1095/biolreprod64.1.171. PMid:11133672.

Magalhães DM, Duarte AB, Araújo VR, Brito IR, Soares TG, Lima IM, Lopes CA, Campello CC, Rodrigues AP, Figueiredo JR. In vitro production of a caprine embryo from a preantral follicle cultured in media supplemented with growth hormone. Theriogenology. 2011;75(1):182-8. http://doi.org/10.1016/j.theriogenology.2010.08.004. PMid:20875671.

Magalhães-Padilha DM, Andrade PM, Sales ET, Araujo VR, Lima IM, Castro SV, Faustino LR, Lopes CA, Campello CC, Báo SN, Gastal MO, Gastal EL, Figueiredo JR. Effect of sequential medium on in vitro culture of goat ovarian cortical tissue. Anim Reprod Sci. 2012;132(3-4):159-68. http://doi.org/10.1016/j.anireprosci.2012.05.017. PMid:22727672.

Magalhães-Padilha DM, Geisler-Lee J, Wischral A, Gastal MO, Fonseca GR, Eloy YR, Geisler M, Figueiredo JR, Gastal EL. Gene expression during early folliculogenesis in goats using microarray analysis. Biol Reprod. 2013;89(1):19. http://doi.org/10.1095/biolreprod.112.106096. PMid:23759311.

Sá NAR, Araújo VR, Correia HHV, Ferreira ACA, Guerreiro DD, Sampaio AM, Escobar E, Santos FW, Moura AA, Lôbo CH, Ceccatto VM, Campello CC, Rodrigues APR, Leal-Cardoso JH, Figueiredo JR. Anethole improves the in vitro development of isolated caprine secondary follicles. Theriogenology. 2017;89:226-34. http://doi.org/10.1016/j.theriogenology.2015.12.014. PMid:28043356.

Sá NAR, Bruno JB, Guerreiro DD, Cadenas J, Alves BG, Cibin FWS, Leal-Cardoso JH, Gastal EL, Figueiredo JR. Anethole reduces oxidative stress and improves in vitro survival and activation of primordial follicles. Braz J Med Biol Res. 2018;51(8):e7129. http://doi.org/10.1590/1414-431x20187129. PMid:29846431.

Sá NAR, Ferreira ACA, Sousa FGC, Duarte ABG, Paes VM, Cadenas J, Anjos JC, Fernandes CCL, Rosseto R, Cibin FWS, Alves BG, Rodrigues APR, Rondina D, Gastal EL, Figueiredo JR. First pregnancy after in vitro culture of early antral follicles in goats: positive effects of anethole on follicle development and steroidogenesis. Mol Reprod Dev. 2020;87(9):966-77. http://doi.org/10.1002/mrd.23410. PMid:32761832.

Saraiva MV, Rossetto R, Brito IR, Celestino JJ, Silva CM, Faustino LR, Almeida AP, Bruno JB, Magalhães DM, Matos MH, Campello CC, Figueiredo JR. Dynamic medium produces caprine embryo from preantral follicles grown in vitro. Reprod Sci. 2010;17(12):1135-43. http://doi.org/10.1177/1933719110379269. PMid:20926838.

Silva AFB, Morais ANP, Lima LF, Ferreira ACA, Silva RF, Sá NAR, Kumar S, Oliveira AC, Alves BG, Rodrigues APR, Gastal EL, Bordignon V, Figueiredo JR. Trimethylation profile of histones H3 lysine 4 and 9 in late preantral and early antral caprine follicles grown in vivo versus in vitro in the presence of anethole. Mol Reprod Dev. 2023;90(12):810-23. http://doi.org/10.1002/mrd.23700. PMid:37671983.

Silva GM, Rossetto R, Chaves RN, Duarte AB, Araújo VR, Feltrin C, Bernuci MP, Anselmo-Franci JA, Xu M, Woodruff TK, Campello CC, Figueiredo JR. In vitro development of secondary follicles from pre-pubertal and adult goats cultured in two-dimensional or three-dimensional systems. Zygote. 2015;23(4):475-84. http://doi.org/10.1017/S0967199414000070. PMid:24666604.

Silva RF, Lima LF, Ferreira ACA, Silva AFB, Alves DR, Alves BG, Oliveira AC, Morais SM, Rodrigues APR, Santos RR, Figueiredo JR. Eugenol improves follicular survival and development during in vitro culture of goat ovarian tissue. Front Vet Sci. 2022;9:822367. http://doi.org/10.3389/fvets.2022.822367 PMid:35573397.
 


Submitted date:
05/03/2024

Accepted date:
08/26/2024

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