Animal Reproduction (AR)
https://animal-reproduction.org/article/doi/10.1590/1984-3143-AR2025-0061
Animal Reproduction (AR)
ORIGINAL ARTICLE

Effectiveness of peri-conception low dose of a highly gluconeogenic fast-release supplement in a fixed-time insemination program on ovarian and reproductive outcomes in meat goats

Caroline Pessoa da Silva; César Carneiro Linhares Fernandes; Alfredo José Herrera Conde; Camila Muniz Cavalcanti; Felipe Brener Bezerra de Oliveira; Saul Gaudencio Neto; Juliana Paula Martins Alves; Dárcio Ítalo Alves Teixeira; Davide Rondina

http://dx.doi.org/10.1590/1984-3143-AR2025-0061 Anim Reprod, vol.23, n3, e20250061, 2026
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Abstract

This study verified the impact of glycerin supplementation during fixed-time insemination on ovarian and reproductive outcomes in meat goats. Fifty-one Anglo-Nubian crossbred does underwent estrus synchronization with 12 days of CIDR, followed by 0.075 mg of d-cloprostenol and 150 IU of eCG. Thirty-six hours after CIDR removal, 100 μg of GnRH was administered, and 18 h later, insemination (AI) was performed via intrauterine laparoscopy. At CIDR insertion, goats were grouped into the Control Group (n = 25) fed a TMR, and the DGS Group (n = 26), where TMR was supplemented with 100 mL of glycerin from CIDR insertion to two weeks after AI. DGS showed a lower diet intake (-13%; P < 0.001) and higher (+ 5.3%; P = 0.026) glucose levels. In the CIDR interval, DGS pregnant goats (DGSPG), presented in the first wave a higher number of growing follicles (P = 0.035) and greater follicular diameters (P < 0.05). After CIDR removal, the DGSPG exhibited a lesser small follicles (P = 0.016), greater follicle size (P = 0.005), and lower number of corpora lutea (P = 0.031). Pregnancy (32.0% vs. 46.2%) and twinning rates (87.5% vs. 66.7%) were similar in Control and DGS groups (P > 0.05). The control group had a higher proportion of non-pregnant goats that were follicular unresponsive during the CIDR interval (P < 0.01). In pregnant animals, no differences (P > 0.05) were found in fetal biometric measurements, kidding rate, or litter size. Glycerin stimulated follicle growth and CL regression before AI but did not promote reproductive effects post-AI.

Keywords

FTAI, glycerin, follicle, corpus luteum, pregnancy

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Submitted date:
05/15/2025

Accepted date:
05/05/2026

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