Animal Reproduction (AR)
Animal Reproduction (AR)
Conference Paper

Oocyte related factors impacting on embryo quality: relevance for in vitro embryo production

Fabienne Nuttinck

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The outcome of pregnancy is closely linked to early events that occur during the onset of embryogenesis. The first stages in embryonic development are mainly governed by the storage of maternal factors present in the oocyte at the time of fertilisation. In this review, we outline the different classes of oocyte transcripts that may be involved in activation of the embryonic genome as well as those associated with epigenetic reprogramming, imprinting maintenance or the control of transposon mobilisation during preimplantation development. We also report the influence of cumulus-oocyte crosstalk during the maturation process on the oocyte transcriptome and how in vitro procedures can affect these interactions.


cumulus cells, germinal-somatic interactions, maternal RNAs, oocyte maturation, preimplantation development.


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