Animal Reproduction (AR)
https://animal-reproduction.org/article/doi/10.21451/1984-3143-AR2019-0004
Animal Reproduction (AR)
Original Article

Canine fetus immune system at late development

Kelly Cristine Santos Roballo, Aline Fernanda Souza, Valéria Maria Lara, Alessandra Oliveira Pinheiro, Ingrid da Silva Gomes, Rafael Garcia Karam, Daniele dos Santos Martins, Luciana Cristina Machado, Carlos Eduardo Ambrósio

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Abstract

The immune system is mainly responsible for protecting the organism against agents that may interfere in its homeostasis. Thus, understand how this system develops and operates is very important, for create new therapies to assist this system in its operation, such as its failure. In domestic dogs, few studies show how actually occurs the development, maturation and functioning of the immune system. Therefore, this study demonstrates the development and possible activation of it on dog fetus from late gestational period by in situ and microscopic analyzes.

Keywords

development, organs, neonate, lymphocytes.

References

Abbas AK, Lichtman AH, Pillai S. 2014. Cellular and Molecular Immunology. 8th ed. Philadelphia: Saunders, Elsevier. 544p.

Abreu DK, Rodrigues EAF, Monteiro JM, Franciolli AL, Costola-Souza C, Roballo KCS, Ambrósio CE, Miglino MA. 2011. Estudo microscópico e macroscópico, com enfoque radiográfico e de alizarina, no desenvolvimento embrionário e fetal de gatos domésticos (Felis catus) em diferentes idades gestacionais. Pesq Vet Bras, 31(Suppl. 1):57-66.

Alitalo K, Carmeliet P. 2002. Molecular mechanisms of lymphangiogenesis in health and disease. Cancer Cell, 1:219-227.

Bryant BJ, Shifrine M, McNeil C. 1973. Cell mediated immune response in the developing dog. Int Arch Allergy Immunol, 45:937-942.

Evans HE, Sack WO. 1973. Prenatal development of domestic and laboratory mammals: growth curves, external features and selected references. Zentralbl Veterinarmed C, 2:11-45.

Felsburg PJ. 2002. Overview of immune system development in the dog: comparison with humans. Hum Exp Toxicol, 21, 487-492.

Holsapple MP, West LJ, Landreth KS. 2003. Species comparison of anatomical and functional immune system development. Birth Defects Res B Dev Reprod Toxicol, 68:321-334.

Hyttel P, Sinowatz F, Vejlsted M. 2010. Domestic Animal Embryology. 11th ed. Philadelphia: Saunders, Elsevier, 208-215.

Martins DS, Ambrósio CE, Saraiva NZ, Wenceslau CV, Morini AC, Kerkis I, Garcia JM, Miglino MA. 2011. Early development and putative primordial germ cells characterization in dogs. Reprod Domest Anim, 46:62-66.

Miglino MA, Ambrosio CE, Martins DS, Wenceslau CV, Pfarrer C, Leiser R. 2006. The carnivore pregnancy: the develop- ment of the embryo and fetal membranes. Theriogenology, 66:1699-1702.

Moore KL, Persaud V. 2008. Embriologia Clínica, 8th ed. Rio de Janeiro: Elsevier, 536pp.

Pieri NC, Souza AF, Casals JB, Roballo KCS, Ambrósio CE, Martins DS. 2015. Comparative Development of Embryonic Age by Organogenesis in Domestic Dogs and Cats. Reprod Domest Anim, 50:625-631.

Pretzer SD. 2008. Canine embryonic and fetal development: a review. Theriogenology, 70:300-303.

Roballo KC, Ercolin AC, Casals JB, Pieri NC, Barreto RS, Illera MJ, Martins DS, Miglino MA, Ambrósio CE. 2013. Domestic carnivore’s development: detec- tion of Oct-4, a pluripotency marker, in pharyngeal arches. Reprod Domest Anim, 48:41-43.

Solomon JB. 1970. Unification of foetal and neonatal immunology. Nature, 29:895-897.

Tizard IR. 2014. Veterinary Immunology. 9th ed. Philadelphia: Saunders, Elsevier, 568p.

Yeager AE, Concannon PW. 1995. Ultrasonography of the reproductive tract of the female dog and cat. In: Bonagura, JD, Kirk RW. (Ed.). Kirk’s current veterinary therapy: XII small animal practice. 12 ed. Philadelphia: Saunders, p.1040-1051.

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