Animal Reproduction (AR)
Animal Reproduction (AR)
Original Article

Morphological features of the uterus during postnatal development in the West African Dwarf goat (Capra hircus)

Clifford Nwabugwu Abiaezute, Innocent Chima Nwaogu, Chidozie Nwabuisi Okoye

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The knowledge of the age at which the West African Dwarf (WAD) goat attains puberty could be exploited to improve this breed of goat and intensify production. The objective of this study was to highlight the postnatal developmental morphology of the uterine tissues of the WAD goat from birth to 28 weeks of age. Fifty WAD goat kids were obtained and grouped into 10 groups of 5 goats per group from day old to week 28. The uterine tissues of euthanized goats were dissected out and examined grossly. Thereafter fixed uterine tissues were prepared for light microscopy and stained with haematoxylin and eosin. Histological images of the uterine tissues were captured with a moticam camera. The length and weight of the uterine horns increased significantly (P < 0.05) from birth to week 28 respectively. The uterine horn was shaped like a ram’s horn. Internally, caruncles were prominent at birth and were regularly arranged in the uterine horn but irregularly arranged in the uterine body. Caruncles were absent in the cranial one third of the uterine horns. Histologically, the uterine horn and uterine body were similar. The endometrium was very cellular at birth without any form of glandular development, while the myometrium and the stratum vasculare were ill defined. Endometrial glands were first observed at week 1. The pseudostratified columnar epithelium of the mucosa at birth changed to simple columnar by week 12. The endometrium and the myometrium were well developed by week 12. In conclusion, the uterus of WAD goat at week 12 appeared similar to the uterus of an adult WAD goat indicating that this goat probably attains puberty earlier than the five - seven months previously reported.


caruncles, endometrial glands, myometrium, postnatal development, West African Dwarf goat.


Abdel Aziz M. 2010. Present stature of the world goat populations and their productivity. Lohman Inf, 45:42-52.

Abd-Elnaeim MMM. 2008. Scanning electron microscopic study on the cyclic goat uterus with special reference to the microvascular architecture of the uterine caruncles. J Agric Vet Sci Qassim Univ, 1:21-32 Abiaezute CN, Nwaogu IC. 2015. Postnatal development of the vagina in West African Dwarf goat (Capra hircus). J Cell Anim Biol, 9:31-37.

Abiaezute CN; Nwaogu IC, Igwebuike UM. 2017. Evaluation of the morphological features of the uterine tubes during postnatal development in West African Dwarf goats (Capra hircus). Vet Res For, 8:1-6 Adigwe PI, Fayemi O. 2005. A Biometric study of the reproductive tract of the Red Sokoto (Maradi) goats of Nigeria. Pak Vet J, 25:149-150.

Akusu MO, Osuagwuh AIA, Akpokodje JU, Egbunike GN. 1986. Ovarian activities of the West African Dwarf goat (Capra hircus) during oestrus. J Reprod Fertil, 78:459-462.

Akusu MO. 1994. The effect of plane of nutrition on vital reproduction statistics of west african dwarf goats. animal reproduction. In: Proceedings of a Regional Seminar. International Foundation for Science (IFS), Niamey, Niger. Niamey: IFS/University of Niamey. pp. 27-34.

Al-Hozab A, Basiouni G. 1999. Onset of puberty in Hebsi and Zomri goats as monitored by plasma progesterone concentrations. J Appl Anim Res, 15:69- 74.

Amoroso ES. 1952. Placentation. In: Parkes AS (Ed.). Marshall's Physiology of Reproduction. 3rd ed. London, UK: Longmans Green. pp. 127-316.

Atkinson BA, King GJ, Amoroso EC. 1984. Development of the caruncular and intercaruncular regions in the bovine endometrium. Biol Reprod, 30:763-764.

Banks WJ. 1993. Applied Veterinary Histology. 3rd ed. St. Louis, MO: Mosby. pp. 446-468.

Bartol FF, Wiley AA, Coleman DA, Wolfe DF, Riddell MG. 1988a. Ovine uterine morphogenesis: effects of age and progestin administration and withdrawal on neonatal endometrial development and DNA synthesis. J Anim Sci, 66:3000-3009.

Bartol FF, Wiley AA, Goodlett DR. 1988b. Ovine uterine morphogenesis: histochemical aspects of endometrial development in the foetus and neonate. J Anim Sci, 66:1303-1313.

Bartol FF, Wiley AA, Spencer TE, Vallet JL, Christenson RK. 1993. Early uterine development in pigs. J Reprod Fertil, 48:99-116.

Bartol FF, Wiley AA, Floyd JG, Ott TL, Bazer FW, Gray CA, Spencer TE. 1999. Uterine differentiation as a foundation for subsequent fertility. J Reprod Fertil, 54:287-302.

Bartol FF, Wiley AA, Bagnell CA. 2008. Epigenetic programming of porcine endometrial function and the lactocrine hypothesis. Reprod Domest Anim, 43:273- 279.

Bazer FW. 1975. Uterine protein secretions: relationship to development of the conceptus. J Anim Sci, 41:1376-1382.

Budras K, Habel RE. 2003. Bovine Anatomy: an illustrated text. Hannover, Germany: Schlutersche. pp. 86-88.

Bukar MM, Amin JD, Sivachelvan MN, Ribadu AY. 2006. Postnatal histological development of the ovaries and uterus and the attainment of puberty in female kid goats. Small Rumin Res, 65:200-208.

Chiboka O, Somade B, Montsama G. 1988. Reproduction of West African Dwarf Goats: a summary of research work at Ile-Ife, Nigeria. In: Smith OB, Bosman HG (Ed.) Goat Production in Humid Tropics. Wageningen: Pudoc. 1988. pp. 125-136.

Cooke SC, Spencer TS, Bartol FF, Hayashi K. 2013. Uterine glands: development, function and experimental model systems. Mol Hum Reprod, 19:547-558.

Desjardins C, Hafs HD. 1969. Maturation of bovine female genitalia from birth through puberty. J Anim Sci, 28:502-507.

Devendra G, Burns M. 1983. Goat Production in the Tropics. 2nd ed. Farnham Royal, Slough, UK: Commonwealth Agricultural Bureaux. pp. 74-89.

Devendra C. 1992. Goats and rural prosperity. In: PreConference Proceedings. Vth. International Conference on Goats, New Delhi, India. New Delhi: IASR. pp. 6-25.

Dyce KM, Sack WO, Wensing CJG. 2002. Veterinary Anatomy. 3rd ed. Philadelphia, PA: Saunders. pp. 637- 639.

Gonzalez G, Behringer RR. 2009. Dicer is required for female reproductive tract development and fertility in the mouse. Mol Reprod Dev, 76:678-688.

Gray CA, Bazer FW, Spencer TE. 2001a. Effects of neonatal progestin exposure on female reproductive tract structure and function in the adult ewe. Biol Reprod, 64:797-804.

Gray CA, Johnson GA, Bartol FF, Tarleton BJ, Wiley AA, Bazer FW, Spencer TE. 2001b. Developmental biology of uterine glands. Biol Reprod, 65:1311-1323.

Greyling JPC. 2000. Reproduction traits in the Boer goat doe. Small Rumin Res, 36:171-177.

Habel RE. 1989. Guide to Dissection of Domestic Ruminants. New York, NY: Published by Robert E.

Habel. 4th ed. pp. 95-105 Hayashi K, O’Connell AR, Juengel JL, McNatty KP, Davis GH, Bazer FW, Spencer TE. 2008. Postnatal uterine development in inverdale ewe lamb. Reproduction, 135:357-365.

Igwebuike UM. 2009. A review of uterine structural modifications that influence conceptus implantation and development in sheep and goats. Anim Reprod Sci, 112:1-7.

Igwebuike UM, Ezeasor DN. 2013. The morphology of placentomes and formation of chorionic villous trees in West African Dwarf goats (Capra hircus). Vet Arh, 83:312-321.

Jainudeen MR, Wahid H, Hafez ESE. 2000. Sheep and goats. In: Hafez ESE, Hafez B (Ed.). Reproduction in Farm Animals. 7th ed. Philadelphia, PA: Lippincott Williams and Wilkins. pp. 170-181.

Katare B, Singh G, Kumar P, Gahlot PK. 2015. Histomorphological studies on uterus of goat (Capra hircus) during follicular and luteal phase. Indian J Vet Anat, 27:47-48.

Kennedy JP, Worthington CA, Cole ER. 1974. The postnatal development of the ovary and uterus of the Merino lamb. J Reprod Fertil, 36:275-282 Khanum SA, Hussain M, Ali M, Kausar R, Cheema AM. 2000. Age at puberty in female dwarf goat kids and eustrous cycle length on the basis of hormones. Pak Vet J, 20:71-76.

Kirkpatrick RL, Akindele Z. 1974. Reproduction in West African Dwarf goats. J Anim Sci, 39(1):163.

Kobayashi A, Behringer RR. 2003. Developmental genetics of the female reproductive tract in mammals. Nat Rev Genet, 4:969-980.

Kurita T, Nakamura H. 2008. Embryology of the uterus. In: Aplin JD, Fazleabas AT, Giudice LC (Ed.). Endometrium. London, UK: Informa Ltd. pp. 1-8.

Lyngest O. 1968. Studies on reproduction in the goat. Acta Vet Scand, 9:208-221.

Maina JA. 2002. Legal framework for the advancement and protection of the Veterinary profession in Nigeria. In: Proceedings at the 39th Nigerian Veterinary Medical Association Conference, Sokoto, Nigeria. Sokoto: NVMA. pp. 10-13.

Michel G, Rabie FO. 1991. Histological study of postnatal development of the uterus of dwarf goat Archiv Exp Vet, 45:15-20.

Oni OO. 2002. Breeds and genetic improvement of small ruminants (sheep and goats). In: Lakpini CAM, Adamu AM, Ehoche OW, Gefu JO (Ed.). Manual for Small Ruminant Production in Nigeria. Zaria National Animal Production Research Institute. 97 pp.

Otchere EO, Nimo MC. 1975. Observations of reproductive behaviour in the West African Dwarf goat. Ghana J Agric Sci, 8:187-190 Pfarrer C, Ebert B, Miglino MA, Klisch K, Leiser R. 2001. The three-dimensional feto-maternal vascular interrelationship during early bovine placental development: a scanning electron microscopical study. J Anat, 198:691-702.

Samuelson AD. 2007. Textbook of Veterinary Histology. St. Louis, MO: Saunders. pp. 443-486 Shalini S, Sharma DN. 2004. Micromorphology and histochemistry of uterus of Gaddi goats during reproduction and senility. Indian J Anim Res, 38:117- 120.

Simplicio AA, Pereira-de-Figueiredo EA, Riera GS, Foote WC. 1990. Puberty in four genotypes of female goats in Northeast Brazil. Pesq Agropec Bras, 25:455- 459

Singh GK, Prakash P. 1990. Effect of age on the morphological changes in the uterus of goat. Indian J Anim Sci, 60:838-839

Sivachelvan MN, Amin JD, Turaki UA. 2002. Some developmental features of female fetal reproductive organs of sahel goats. Sahel J Vet Sci, 1:11-16.

Smith MC. 1986. Caprine reproduction. In: Marrow DA (Ed.). Current Therapy in Theriogenology. Philadelphia, PA: Saunders. pp. 577-579.

Spencer TE, Hayashi K, Hu J, Carpenter KD. 2005. Comparative developmental biology of the mammalian uterus. Curr Top Dev Biol, 68:85-122.

Spencer TE, Dunlap KA, Filant J. 2012. Comparative developmental biology of the uterus: insights into mechanisms and developmental disruption. Mol Cell Endocrinol, 354:34-53.

Stevens DH, Burton GJ, Samuel AC. 1981. Histology and electron microscopy of sheep placental membranes. Placenta, 2:11-34.

Stewart MD, Johnson GA, Gray CA, Burghardt RC, Schuler LA, Joyce MM, Bazer FW, Spencer, TE. 2000. Prolactin receptor and uterine milk protein expression in the ovine endometrium during the estrous cycle and pregnancy. Biol Reprod, 62:1779-1789 Taylor RE, Field TG. 2001. Goat breeding, feeding and management. In: Taylor RE, Field TG. Scientific Farm Animal Production. 7th ed. Upper Saddle River, NJ: Prentice-Hall. pp. 644-670.

Udoh EP, Egbunike GN, Sokunbi OA. 2010. Morphometric and biochemical characteristics of reproductive tract of post-pubertal West African Dwarf goats: a preliminary investigation. Nig J Agric Food Environ, 6:6-12.

Wiley AA, Bartol FF, Barron DH. 1987. Histogenesis of the ovine uterus. J Anim Sci, 64:1262- 1269.

Wimsatt WA. (1950. New histological observations on the placenta of the sheep. Am J Anat, 87:391-436

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