Pre-TAI protocol strategies to increase reproductive efficiency in beef and dairy cows
José Nélio de Sousa Sales, , Luiz Manoel Souza Simões, Raphael Evangelista Orlandi, Eduardo Alves Lima, Ana Paula Castro Santos, Miguel Pizzolante Bottino, Luiz Augusto Capellari Leite da Silva, José Camisão de Souza, Marcelo Maronna Dias, João Paulo Martinelli Massoneto, Luiz Antônio Scandiuzzi Jr., Bruno Gonzalez Freitas, Bruna Martins Guerreiro, Michele Ricieri Bastos
Abstract
Ovulation synchronization protocols are well established in beef and dairy cows. However, the protocol response rate is around 70-90%. In beef cows, factors such as inadequate nutrition and calf presence negatively impact the response of progesterone (P4)/estradiol-based ovulation synchronization protocols by interfering with GnRH release and consequently reducing LH pulsatility and final follicular development. In dairy cows, protocols based on GnRH and prostaglandin (Ovsynch) are the most widely used in the world. However, the efficiency of Ovsynch is dependent on the presence of a large follicle at the time of administration of the first GnRH. In these ovulation synchronization protocols, pre-synchronization protocols (Prostaglandins, Double Ovsynch and P4synch) are usually attempted in an effort to increase responses. Thus, the objective of this review was to discuss pre-ovulation synchronization strategies (administration of injectable P4 or energetic/protein supplementation or presynchronization with intra-vaginal progesterone devices) aiming to increase the LH pulsatility in beef cows or induce the formation of a GnRH-responsive follicle at the beginning of the Ovsynch protocol in dairy cows.
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References
Anderson LH, Day ML. 1998. Current Concepts on the Control of Puberty in Cattle. J Anim Sci, 76:1-15.
Ayres H, Ferreira RM, Cunha AP, Araujo RR, Wiltbank MC. 2013. Double-Ovsynch in high-producing dairy cows: effects on progesterone concentrations and ovulation to GnRH treatments. Theriogenology, 79:159-164.
Ayres H, Ferreira RM, Torres-Junior JR, Demetrio CG, Sa Filho MF, Gimenes LU, Penteado L, D'Occhio MJ, Baruselli PS. 2014. Inferences of body energy reserves on conception rate of suckled Zebu beef cows subjected to timed artificial insemination followed by natural mating. Theriogenology, 82:529-536.
Baruselli PS, Reis EL, Marques MO, Nasser LF, Bo GA. 2004. The use of hormonal treatments to improve reproductive performance of anestrous beef cattle in tropical climates. Anim Reprod Sci, 82-83:479-486.
Baruselli P, Sales JN, Sala R, Viera LM, Sá Filho M. 2012. History, evolution and perspectives of timed artificial insemination programs in Brazil. Anim Reprod, 9:139-152.
Baruselli P, Ferreira R, Colli M, Elliff F, Sá Filho M, Vieira L, Freitas B. 2017. Timed artificial insemination: Current challenges and recent advances in reproductive efficiency in beef and dairy herds in Brazil. Anim Reprod, 14:558-571.
Beam SW, Butler WR. 1998. Energy balance, metabolic hormones, and early postpartum follicular development in dairy cows fed prilled lipid. J Dairy Sci, 81:121-131.
Bello NM, Steibel JP, Pursley JR. 2006. Optimizing ovulation to first GnRH improved outcomes to each hormonal injection of ovsynch in lactating dairy cows. J Dairy Sci, 89:3413-3424.
Cerri RL, Rutigliano HM, Bruno RG, Santos JE. 2009. Progesterone concentration, follicular development and induction of cyclicity in dairy cows receiving intravaginal progesterone inserts. Anim Reprod Sci, 110:56-70.
Chebel RC, Santos JE, Cerri RL, Rutigliano HM, Bruno RG. 2006. Reproduction in dairy cows following progesterone insert presynchronization and resynchronization protocols. J Dairy Sci, 89:4205-4219.
Crowe MA, Diskin MG, Williams EJ. 2014. Parturition to resumption of ovarian cyclicity: comparative aspects of beef and dairy cows. Animal, 1:40-53.
Darwash AO, Lamming GE, Wooliams JA. 2010. The phenotypic association between the interval to post-partum ovulation and traditional measures of fertility in dairy cattle. Anim Sci, 65:9-16.
Day ML. 2004. Hormonal induction of estrous cycles in anestrous Bos taurus beef cows. Anim Reprod Sci, 82-83:487-494.
DiCostanzo A, Williams JE, Keisler DH. 1999. Effects of short- or long-term infusions of acetate or propionate on luteinizing hormone, insulin, and metabolite concentrations in beef heifers. J Anim Sci, 77:3050-3056.
Diskin MG, Mackey DR, Roche JF, Sreenan JM. 2003. Effects of nutrition and metabolic status on circulating hormones and ovarian follicle development in cattle. Anim Reprod Sci, 78:345-370.
El-Zarkouny SZ, Cartmill JA, Richardson AM, Medina-Britos MA. 2001. Presynchronization of estrous cycles in dairy cows before ovsynch + CIDR and resynchronization of repeat estrus using the CIDR. Kansas Agricultural Experiment Station Research Reports, 0:52-54.
Ferreira RM, Ayres H, Sales JN, Souza AH, Rodrigues CA, Baruselli PS. 2013. Effect of different doses of equine chorionic gonadotropin on follicular and luteal dynamics and P/AI of high-producing Holstein cows. Anim Reprod Sci, 140:26-33.
Fike KE, Day ML, Inskeep EK, Kinder JE, Lewis PE, Short RE, Hafs HD. 1997. Estrus and luteal function in suckled beef cows that were anestrous when treated with an intravaginal device containing progesterone with or without a subsequent injection of estradiol benzoate. J Anim Sci, 75:2009-2015.
Giordano JO, Wiltbank MC, Guenther JN, Pawlisch R, Bas S, Cunha AP, Fricke PM. 2012. Increased fertility in lactating dairy cows resynchronized with Double-Ovsynch compared with Ovsynch initiated 32 d after timed artificial insemination. J Dairy Sci, 95:639-653.
Grimard B, Humblot P, Ponter AA, Mialot JP, Sauvant D, Thibier M. 1995. Influence of postpartum energy restriction on energy status, plasma LH and oestradiol secretion and follicular development in suckled beef cows. J Reprod Fertil, 104:173-179.
Herlihy MM, Giordano JO, Souza AH, Ayres H, Ferreira RM, Keskin A, Nascimento AB, Guenther JN, Gaska JM, Kacuba SJ, Crowe MA, Butler ST, Wiltbank MC. 2012. Presynchronization with Double-Ovsynch improves fertility at first postpartum artificial insemination in lactating dairy cows. J Dairy Sci, 95:7003-7014.
Hess B, Lake SL, Scholljegerdes EJ, Weston TR, Nayigihugu V, Molle JDC, Moss GE. 2005. Nutritional controls of beef cow reproduction. J Anim Sci, 83:90-106.
Inskeep EK, Braden TD, Lewis PE, Garcia-Winder M, Niswender GD. 1988. Receptors for luteinizing hormone and follicle-stimulating hormone in largest follicles of postpartum beef cows. Biol Reprod, 38:587-591.
Ireland JJ, Roche JF. 1982. Development of antral follicles in cattle after prostaglandin-induced luteolysis: changes in serum hormones, steroids in follicular fluid, and gonadotropin receptors. Endocrinology, 111:2077-2086.
Jolly PD, McDougall S, Fitzpatrick LA, Macmillan KL, Entwistle KW. 1995. Physiological effects of undernutrition on postpartum anoestrus in cows. J Reprod Fertil Suppl, 49:477-492.
Lucy MC, Billings HJ, Butler WR, Ehnis LR, Fields MJ, Kesler DJ, Kinder JE, Mattos RC, Short RE, Thatcher WW, Wettemann RP, Yelich JV, Hafs HD. 2001. Efficacy of an intravaginal progesterone insert and an injection of PGF2α for synchronizing estrus and shortening the interval to pregnancy in postpartum beef cows, peripubertal beef heifers, and dairy heifers. J Anim Sci, 79:982-995.
Malven PV, Parfet JR, Gregg DW, Allrich RD, Moss GE. 1986. Relationships among concentrations of four opioid neuropeptides and luteinizing hormone-releasing hormone in neural tissues of beef cows following early weaning. J Anim Sci, 62:723-733.
McDougall S, Burke CR, MacMillan KL, Williamson NB. 1995. Patterns of follicular development during periods of anovulation in pasture-fed dairy cows after calving. Res Vet Sci, 58:212-216.
McShane TM, Petersen SL, McCrone S, Keisler DH. 1993. Influence of food restriction on neuropeptide-Y, proopiomelanocortin, and luteinizing hormone-releasing hormone gene expression in sheep hypothalami. Biol Reprod, 49:831-839.
Mihm M, Baguisi A, Boland MP, Roche JF. 1994. Association between the duration of dominance of the ovulatory follicle and pregnancy rate in beef heifers. J Reprod Fertil, 102:123-130.
Montiel F, Ahuja C. 2005. Body condition and suckling as factors influencing the duration of postpartum anestrus in cattle: a review. Anim Reprod Sci, 85:1-26.
Moreira F, Orlandi C, Risco CA, Mattos R, Lopes F, Thatcher WW. 2001. Effects of presynchronization and bovine somatotropin on pregnancy rates to a timed artificial insemination protocol in lactating dairy cows. J Dairy Sci, 84:1646-1659.
Mulliniks JT, Kemp ME, Endecott RL, Cox SH, Roberts AJ, Waterman RC, Geary TW, Scholljegerdes EJ, Petersen MK. 2013. Does beta-hydroxybutyrate concentration influence conception date in young postpartum range beef cows? J Anim Sci, 91:2902-2909.
Navanukraw C, Redmer DA, Reynolds LP, Kirsch JD, Grazul-Bilska AT, Fricke PM. 2004. A modified presynchronization protocol improves fertility to timed artificial insemination in lactating dairy cows. J Dairy Sci, 87:1551-1557.
Orlandi RE, Simões LMS, Bottino MP, Santos APC, Lima EA, Massoneto JPM, Scandiuzzi LA, Jr., Pádua PHBM, Sales JNS. 2018. Energy and protein supplementation on follicular growth and pregnancy rate of Bos indicus lactating cows submitted to FTAI in a breeding season of 110 days. Anim Reprod, 15:329. (Abstract).
Ospina PA, Nydam DV, Stokol T, Overton TR. 2010. Associations of elevated nonesterified fatty acids and beta-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern United States. J Dairy Sci, 93:1596-1603.
Peres RFG, Carvalho R, Graff H, Furlan Junior JH, Rodrigues ADP, Franco GA, Keisler DH, Smith MF, Pohler KG, Vasconcelos JLM. 2016. Corn supplementation during 41 days after the begginning of TAI protocol and its effects on metabolic hormones and reproductive performance of Nelore females. Anim Reprod, 13:382. (Abstract).
Pescara JB, Sá Filho OG, Losi TC, Cooke RF, Vasconcelos JLM. 2010. Serum progesterone concentration and conception rate of beef cows supplemented with ground corn after a fixed-time artificial insemination protocol. Arq Bras Med Vet e Zootec, 62:130-135.
Pursley JR, Mee MO, Wiltbank MC. 1995. Synchronization of ovulation in dairy cows using PGF2alpha and GnRH. Theriogenology, 44:915-923.
Revah I, Butler WR. 1996. Prolonged dominance of follicles and reduced viability of bovine oocytes. J Reprod Fertil, 106:39-47.
Rhodes FM, Burke CR, Clark BA, Day ML, Macmillan KL. 2002. Effect of treatment with progesterone and oestradiol benzoate on ovarian follicular turnover in postpartum anoestrous cows and cows which have resumed oestrous cycles. Anim Reprod Sci, 69:139-150.
Sa Filho OG, Meneghetti M, Peres RF, Lamb GC, Vasconcelos JL. 2009. Fixed-time artificial insemination with estradiol and progesterone for Bos indicus cows II: strategies and factors affecting fertility. Theriogenology, 72:210-218.
Sales JNS, Crepaldi GA, Girotto RW, Souza AH, Baruselli PS. 2011. Fixed-time AI protocols replacing eCG with a single dose of FSH were less effective in stimulating follicular growth, ovulation, and fertility in suckled-anestrus Nelore beef cows. Anim Reprod Sci, 124:12-18.
Sales JNS, Carvalho JB, Crepaldi GA, Cipriano RS, Jacomini JO, Maio JR, Souza JC, Nogueira GP, Baruselli PS. 2012. Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol. Theriogenology, 78:510-516.
Sales JNS, Carvalho JB, Crepaldi GA, Soares JG, Girotto RW, Maio JR, Souza JC, Baruselli PS. 2015. Effect of circulating progesterone concentration during synchronization for fixed-time artificial insemination on ovulation and fertility in Bos indicus (Nelore) beef cows. Theriogenology, 83:1093-1100.
Sales JNS, Bottino MP, Silva LA, Girotto RW, Massoneto JP, Souza JC, Baruselli PS. 2016. Effects of eCG are more pronounced in primiparous than multiparous Bos indicus cows submitted to a timed artificial insemination protocol. Theriogenology, 86:2290-2295.
Samadi F, Phillips NJ, Blache D, Martin GB, D'Occhio MJ. 2013. Interrelationships of nutrition, metabolic hormones and resumption of ovulation in multiparous suckled beef cows on subtropical pastures. Anim Reprod Sci, 137:137-144.
Santos APC, Orlandi RE, Bottino MP, Simões LMS, Lima EA, Silva AG, Guerreiro BM, Bastos MR, Freitas BG, Bertoncini FLS, Santos JA, Sales JNS. 2018. Effect of pre-exposition to injectable long acting progesterone on pregnancy rates of suckled beef cows submitted to the estrous synchronization protocol. Anim Reprod, 15:328. (Abstract).
Schillo KK. 1992. Effects of dietary energy on control of luteinizing hormone secretion in cattle and sheep. J Anim Sci, 70:1271-1282.
Silva L, Simoes LMS, Bottino MP, Santos APC, Santos G, Martinez IYH, Souza JC, Baruselli PS, Sales JNS. 2018. Presynchronization by induction of a largest follicle using a progesterone device in GnRH-based-ovulation synchronization protocol in crossbred dairy cows. Theriogenology, 119:233-237.
Simões LMS, Orlandi RE, Massoneto JPM, Scandiuzzi LA, Jr, Freitas BG, Bastos MR, Souza JC, Sales JNS. 2018. Exposure to progesterone previous to the protocol of ovulation synchronization increases the follicular diameter and the fertility of suckled Bos indicus cows. Theriogenology, 116:28-33.
Souza AH, Ayres H, Ferreira RM, Wiltbank MC. 2008. A new presynchronization system (Double-Ovsynch) increases fertility at first postpartum timed AI in lactating dairy cows. Theriogenology, 70:208-215.
Vasconcelos JL, Silcox RW, Rosa GJ, Pursley JR, Wiltbank MC. 1999. Synchronization rate, size of the ovulatory follicle, and pregnancy rate after synchronization of ovulation beginning on different days of the estrous cycle in lactating dairy cows. Theriogenology, 52:1067-1078.
Williams GL, Gazal OS, Vega GAG, Stanko RL. 1996. Mechanisms regulating suckling-mediated anovulation in the cow. Anim Reprod Sci, 42:289-297.
Wiltbank MC, Baez GM, Cochrane F, Barletta RV, Trayford CR, Joseph RT. 2015. Effect of a second treatment with prostaglandin F2alpha during the Ovsynch protocol on luteolysis and pregnancy in dairy cows. J Dairy Sci, 98:8644-8654.
Yavas Y, Walton JS. 2000. Postpartum acyclicity in suckled beef cows: a review. Theriogenology, 54:25-55.
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